| 名稱 | TP53 p.R248Q Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10140 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | TP53 p.R248Q Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- 三陰性乳腺癌的一個(gè)突破口——BRCA基因檢測(cè)？
- 甲基丙二酸血癥（MMA）標(biāo)準(zhǔn)品上新
- STEAP1/2的細(xì)胞模型
- 一箭雙雕——IL-4R靶點(diǎn)和IL-4/IL-13雙重阻斷藥篩細(xì)胞模型
- ATCC細(xì)胞株所用培養(yǎng)基有何要求？
- 官宣！Ba/F3激酶穩(wěn)定細(xì)胞株&科佰激酶篩選平臺(tái)
- IL6藥物細(xì)胞篩選模型
- 心衰治療靶點(diǎn)：BNP/NPR1
- 從諾輝財(cái)報(bào)看甲基化市場(chǎng)，科佰生物助力甲基化標(biāo)準(zhǔn)品的開發(fā)
- IL9細(xì)胞篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10140TP53 p.R248Q Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10140 | |
| Format | Genomic DNA |
| Description | TP53 R248Q is a hotspot mutation that lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). R248Q results in decreased transactivation of Tp53 targets and interference with wild-type Tp53 transactivation in cell culture, as well as increased Akt activation and enhanced tumor onset and growth in mouse models (PMID: 23538418, PMID: 16861262). |
| Technical Data | |
| DNA Change: | c.743G>A |
| AA Change | p.R248Q |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000269305 |
| Cosmic ID | COSM10662 |
| Chr position(GRCh37) | chr17:7577538 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)